In this issue: R.T. Silver, C. Harrison,  R. Mesa,  H.C. Hasselbalch, How I treat MPNs…  J.J. Michiels, Aspirin, Platelets and Thrombosis

 H.C. Hasselbalch, Interferon instructions for my patients

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The effect of interferon on polycythemia vera bone marrow over an eight year period

Slides, courtesy of Dr. Hans Hasselbalch


(A) Bone marrow histomorphology from a patient with early prefibrotic polycythemia vera at diagnosis in 1996. (B) Typical hypercellular polycythemia vera with clustered large pleiomorphic megakaryocytes. (C) Normal cellular bone marrow in complete hematological and molecular remission with megakaryocytes of normal size and morphology after 8 years of treatment with interferon α-2b treatment.

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 © MPN Quarterly Journal, 2013. This work is licensed under a Creative Commons Attribution-NonCommercial No-Derivs 3.0 Unported License.