In this issue: R.T. Silver, C. Harrison, R. Mesa, H.C. Hasselbalch, How I treat MPNs… J.J. Michiels, Aspirin, Platelets and Thrombosis…
H.C. Hasselbalch, Interferon instructions for my patients
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The effect of interferon on polycythemia vera bone marrow over an eight year period
Slides, courtesy of Dr. Hans Hasselbalch
(A) Bone marrow histomorphology from a patient with early prefibrotic polycythemia vera at diagnosis in 1996. (B) Typical hypercellular polycythemia vera with clustered large pleiomorphic megakaryocytes. (C) Normal cellular bone marrow in complete hematological and molecular remission with megakaryocytes of normal size and morphology after 8 years of treatment with interferon α-2b treatment.

© MPN Quarterly Journal, 2013. This work is licensed under a Creative Commons Attribution-NonCommercial No-Derivs 3.0 Unported License. MPNquarterly@gmail.com
3 Comments
Post a commentHi Susan,
I had PV for twenty two years and converted to MF in 2012. I have been on INFN since 2012 and it has been fantastic my counts are stable now. Will it last? Who knows but my MPN Fog is gone as well . When other Doctors say there is no evidence INFN works I laugh because that is just not true. I did have to purse Stanford to put me on INFN they did not want to do it but they are thawing there due to my results. If you or sister would like to speak with me I can forward you an email address with my contact information.
Printed down and read = such GOOD INFO, Zhen! Thanks for YOU and the Doctors! Taking a copy to my doctor! Thanks for all your hard work getting the latest info to us -keeping us informed.
What about interferon with MF Milofibrosis? My sister had PRV and was told not to worry ” put it on the back burner of your life”
Well within 6 months it has become MF. The general response from doctors around Pegasys or interferon and it’s
possible affect on MF seems that there is no proof. Furthermore it takes time to see the results.
Any comments would be well appreciated. Susan Telford